Xiao Hua, Lancaster University
Atomic structure study of energy materials via in-house X-ray total scattering
Many energy materials exhibit atomic imperfections like distortion and disorder, which are key to their functionality. Pair distribution function (PDF) analysis via X-ray total scattering experiment is a powerful technique for resolving atomic complexity but typically requires large user facilities. This Fellowship aims to innovate in-house PDF instrumentation, enabling routine atomic structure characterization of energy materials used in catalysis and batteries, with support from industrial partners.
Dr Andy Chetwynd, University of Liverpool
Urine Proteome and Glycome Analysis in Kidney Disease
The development of LC-MS and CE-MS based proteomic and glycomic analysis for urine in clinical studies offers a great opportunity to help better understand and combat the growing burden of kidney disease.
LC and CE separations are orthogonal separation techniques combining both will allow a more comprehensive coverage of the proteome and glycome and in the case of CE reduce the environmental burden of analysis by eliminating organic solvents and reducing flow rates.
Dr Michael Cotterell, University of Oxford
Kinetics of Photobleaching in Aerosol Particles
Understanding how light interacts with aerosol particles is central to several areas, including in atmospheric chemistry. For example, a large fraction of atmospheric aerosol particles contain molecules that absorb light in the short visible spectrum and undergo photobleaching. The rates of photobleaching for these molecules lack characterisation in aerosols. This project will use laser-based spectroscopy to quantify bleaching rates in single aerosol particles levitated using electrical fields. Our measurements will explore the role of viscosity, water content, and particle size on the rates of photobleaching.
Mohamed Sharafeldin, University College Cork
Diagnostic Applications of CRISPR-Cas Technology
The precise programmability of CRISPR-Cas systems offer a valuable tool to produce innovative biosensors for healthcare applications. My current project explores CRISPR-Cas technology for rapid, highly specific disease diagnostics, integrating addressable electrochemical signal transduction probes within engineered carriers. This approach enables low-cost, point-of-care testing, improving early detection and patient outcomes while advancing precision medicine and decentralized healthcare solutions.
