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Whether you're a large or a small company, purchasing analytical instrumentation is a significant investment. This reference guide helps you understand the process of making informed decisions to ensure you have fit-for-purpose instrument with trained staff to deliver accurate and reliable data.

Working in any kind of laboratory will require the analyst to possess a basic set of practical skills. Measuring mass or volume, and preparing solutions of known concentration, are likely to be everyday activities. In addition, working in a molecular biology laboratory will entail specific considerations related to the nature of the materials being handled.


This guide, prepared with the assistance of members of the AMC Mass Spectrometry Sub-Committee, brings together practical advice to assist LC-MS users avoid many common problems and to develop reliable, quantitative applications as quickly and cheaply as possible.  Achieving…

Check the condition of all glassware before use, taking special care when using equipment such as pipettes and burettes, as the tips can be easily damaged if these items are not stored correctly.

Glassware should be clean and free from dust. To test if an item is clean:

  • Allow water to drain from the item;
  • The absence of discrete droplets of water on the interior surface indicates a clean, dust free interior.

If droplets of water remain on…