Secretariat's Articles (23)

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Whether you're a large or a small company purchasing analytical instrumentation is a significant investment. This reference guide helps you understand the process of making informed decisions to ensure you have fit-for-purpose instrument with trained staff to deliver accurate and reliable data.

 

Over a period of 20 years a number of best practice guides were produced under the UK’s Valid Analytical Measurement programme (VAM).  In the coming months we will be making some of these available on the CAMS website as we start to position…

Working in any kind of laboratory will require the analyst to possess a basic set of practical skills. Measuring mass or volume, and preparing solutions of known concentration, are likely to be everyday activities. In addition, working in a molecular biology laboratory will entail specific considerations related to the nature of the materials being handled.

This guide covers the basic laboratory skills and other measures required to produce valid results in a molecular biology laboratory − results that are not compromised by poor practical technique, possible cross-contamination or non-validated methodology.

This guide, prepared with the assistance of members of the AMC Mass Spectrometry Sub-Committee, brings together practical advice to assist LC-MS users avoid many common problems and to develop reliable, quantitative applications as quickly and cheaply as possible.  Achieving reliable quantitation by LC-MS depends not only on correct use of the instrumentation but also on correct development and use of the entire analytical method.  Extensive advice on aspects such as sample preparation and calibration strategies is included.  Experience shows that many errors in analytical data result not from lack of understanding of the measurement techniques but as a result of simple and avoidable mistakes during their application. …